The following error is extremely common in EDI deployments:
6: Missing or invalid or duplicate Transaction set identifier ‘http://schemas.microsoft.com/BizTalk/EDI/X12/2006#X12_00401_850′
It generally means one of two things:
1. The EDI schema is not deployed properly (or is partially deployed).
2. The schema has been deployed more than once and two (or more) versions of it appear in the GAC.